Description

3-o-Acetyl-26-Hydroxy Cholesterol is a high-purity sterol derivative, a key intermediate in the synthesis of complex bioactive molecules. Its value lies in its defined chemical structure, which serves as a crucial building block for pharmaceutical research and development. This compound is essential for researchers and manufacturers in the pharmaceutical and life science industries, particularly those developing novel steroid-based therapeutics and conducting metabolic pathway studies.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of advanced steroid drugs and hormone analogs.
• Biochemical Research: Used as a standard or reagent in studies of cholesterol metabolism, enzyme activity, and receptor binding assays.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Organic Synthesis: A versatile building block for the chemical modification of the sterol backbone to create novel compounds for screening.
• Metabolite Synthesis: Employed in the preparation of specific cholesterol metabolites for biological evaluation and diagnostic applications.

Basic Information

Product Name	3-o-Acetyl-26-Hydroxy Cholesterol
CAS No.	50681-37-3
Molecular Formula	C₂₉H₄₈O₃
Molecular Weight	444.70 g/mol
Synonyms	26-Hydroxycholesterol 3-acetate; 3β-Acetoxy-26-hydroxycholest-5-ene; (3β,25R)-26-Hydroxycholest-5-en-3-yl acetate; 26-Hydroxy-3β-acetoxycholest-5-ene; Cholest-5-ene-3β,26-diol, 3-acetate; 26-HC 3-acetate
EINECS	Contact for details

Quality Control

Our 3-o-Acetyl-26-Hydroxy Cholesterol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.