Description

2-Aza-1, N6-Ethenoadenosine-3',5'-Cyclic Monophosphate Sodium Salt is a chemically modified, fluorescent analog of cyclic adenosine monophosphate (cAMP). This compound is a critical research tool for studying intracellular signaling pathways, particularly those mediated by cAMP-dependent protein kinases (PKA). It is primarily utilized by researchers in pharmaceutical R&D and academic institutions for biochemical assays, enzyme kinetics studies, and as a probe for investigating nucleotide-binding sites.

Application

• Biochemical Research: As a potent and fluorescent analog of cAMP for studying PKA activation, inhibition, and regulatory mechanisms.
• Enzyme Kinetics & Binding Studies: Used to investigate the binding affinity and specificity of phosphodiesterases (PDEs) and other cAMP-binding proteins.
• Cell Signaling Pathway Analysis: A valuable probe in fluorescence-based assays to visualize and quantify cAMP-mediated signal transduction in live or fixed cells.
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) platforms to identify novel modulators of the cAMP-PKA pathway for drug discovery.
• Diagnostic Assay Development: Serves as a key component in developing sensitive immunoassays or biosensors for cAMP detection.

Basic Information

Product Name	2-Aza-1, N6-Ethenoadenosine-3',5'-Cyclic Monophosphate Sodium Salt
CAS No.	50663-90-6
Molecular Formula	C13H13N6NaO6P
Molecular Weight	418.25 g/mol
Synonyms	2-Aza-1,N6-etheno-cAMP sodium salt; 1,N6-Etheno-2-aza-cAMP sodium salt; 2-Aza-ε-cAMP sodium salt; Fluorescent cAMP analog; ε-2-Aza-cAMP Na+; 8-(2-Aza-1,N6-ethenoadenosine)-3',5'-cyclic monophosphate sodium salt
EINECS	Contact for details

Quality Control

Our 2-Aza-1, N6-Ethenoadenosine-3',5'-Cyclic Monophosphate Sodium Salt is manufactured under strict quality control protocols suitable for research applications. Each batch is analyzed to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided to support your research integrity and reproducibility requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). For long-term storage, consider desiccation and storage under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.