Description

(22E,24R)-Ergosta-5,8,22-Triene-3β-Ol CAS NO 50657-31-3 is a specific, high-purity sterol derivative belonging to the ergostane class, characterized by its unique (22E,24R) stereochemistry and conjugated triene system. This compound serves as a critical advanced intermediate and reference standard for research and development in pharmaceutical and nutraceutical synthesis. It is essential for organizations engaged in the study of sterol metabolism, vitamin D analogs, and the development of novel therapeutic agents. Target industries include pharmaceutical R&D, fine chemical synthesis, and academic research institutions requiring well-defined molecular building blocks.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of complex steroidal drugs and vitamin D analogs.
• Reference Standard: High-purity material for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Biochemical Research: Probe for studying sterol biosynthesis pathways, enzyme mechanisms, and membrane biology.
• Nutraceutical Development: Intermediate in the research and production of specialized ergosterol-derived supplements.
• Fine Chemical Synthesis: Starting material for the preparation of other functionalized ergostane derivatives with tailored biological activity.

Basic Information

Product Name	(22E,24R)-Ergosta-5,8,22-Triene-3β-Ol
CAS No.	50657-31-3
Molecular Formula	C₂₈H₄₄O
Molecular Weight	396.65 g/mol
Synonyms	(22E,24R)-Ergosta-5,8,22-trien-3β-ol; 5,7,22-Ergostatrien-3β-ol; Ergosta-5,8,22-trien-3-ol, (22E,24R)-; 3β-Hydroxy-(22E,24R)-ergosta-5,8,22-triene; (24R)-Ergosta-5,8,22-trien-3β-ol; Dehydroergosterol precursor; 5,8,22-Ergostatrien-3β-ol
EINECS	Contact for details

Quality Control

Our (22E,24R)-Ergosta-5,8,22-Triene-3β-Ol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic methods (NMR, IR, MS) for structural confirmation, to ensure identity, potency, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.