Description

7-Methoxy-α-Oxo-1H-Indole-3-Acetyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. This compound matters for its role as a key building block in the creation of complex heterocyclic molecules, offering precise control over molecular architecture. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of indole-based drug candidates, particularly for neurological and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of new herbicides and plant growth regulators that leverage the indole scaffold.
• Organic Synthesis Building Block: Serves as a versatile reagent for constructing complex heterocyclic compounds in academic and industrial R&D laboratories.
• Material Science Research: Investigated for the development of novel organic electronic materials and specialty dyes.
• Bioconjugation Chemistry: The reactive acid chloride group enables its use in coupling reactions for labeling and modifying biomolecules.

Basic Information

Product Name	7-Methoxy-α-Oxo-1H-Indole-3-Acetyl Chloride
CAS No.	50656-47-8
Molecular Formula	C12H10ClNO3
Molecular Weight	251.67 g/mol
Synonyms	7-Methoxy-α-oxo-1H-indole-3-acetyl chloride; 7-Methoxy-1H-indole-2,3-dione 3-acetyl chloride; 3-(Chloroformylmethyl)-7-methoxy-1H-indole-2-carboxylic acid; 7-Methoxyisatin-3-acetyl chloride; 2-Carboxy-7-methoxyindole-3-acetic acid chloride; 7-Methoxy-2,3-dioxoindoline-3-acetyl chloride; 7-Methoxy-3-(2-chloro-2-oxoethyl)-1H-indol-2(3H)-one
EINECS	Contact for details

Quality Control

Our 7-Methoxy-α-Oxo-1H-Indole-3-Acetyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in common organic solvents (DMF, DMSO, THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.