Description

Fosfomycin Sodim CAS NO 50636-58-3 is the sodium salt form of the broad-spectrum antibiotic fosfomycin. This compound is valued for its unique mechanism of action, inhibiting bacterial cell wall synthesis at an early stage, which makes it effective against a range of Gram-positive and Gram-negative bacteria. It is a critical active pharmaceutical ingredient (API) primarily required by pharmaceutical manufacturers for the production of injectable and oral antibiotic formulations. Its utility extends to veterinary medicine and as a key intermediate in advanced antibiotic synthesis.

Application

• Primary use as an Active Pharmaceutical Ingredient (API) in human antibiotic injectables and oral medications.
• Formulation of veterinary pharmaceutical products for treating bacterial infections in livestock and companion animals.
• Manufacturing of combination drug therapies to combat multi-drug resistant bacterial strains.
• Use in clinical research and development of new antimicrobial agents.
• Intermediate in the synthesis of other fosfomycin derivatives and related antibiotic compounds.
• Component in laboratory microbiology for susceptibility testing and study of bacterial resistance mechanisms.

Basic Information

Product Name	Fosfomycin Sodim
CAS No.	50636-58-3
Molecular Formula	C3H5Na2O4P
Molecular Weight	182.02 g/mol
Synonyms	Fosfomycin Sodium; Fosfomycin Disodium Salt; Sodium Fosfomycin; (3-Methyloxiran-2-yl)phosphonic Acid Disodium Salt; Phosphomycin Sodium; MK-0951 Sodium Salt; FOM-Na; Antibiotic MK-0951 Sodium Salt
EINECS	256-659-6

Quality Control

Our Fosfomycin Sodim is manufactured under strict quality systems to ensure it meets the high standards required for pharmaceutical applications. Each batch is tested against rigorous specifications for identity, purity, and potency. We can supply material compliant with Pharmaceutical Grade standards, and Certificates of Analysis (COA) documenting comprehensive testing results, including assay, related substances, and residual solvents, are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
pH (10% solution)	8.5 - 10.5
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins	< 0.17 IU/mg (for injectable grade)
Microbial Enumeration	Complies with Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.