Description

Halometasone is a synthetic corticosteroid belonging to the glucocorticoid class, recognized for its potent anti-inflammatory and antipruritic properties. This high-purity active pharmaceutical ingredient (API) is critical for formulators requiring reliable and consistent raw material quality for topical dermatological preparations. It is primarily utilized by pharmaceutical manufacturers and R&D institutions focused on developing and producing advanced topical treatments for various skin conditions.

Application

• Topical Corticosteroid Formulations: Primary active ingredient in creams, ointments, and lotions for treating inflammatory skin disorders.
• Dermatological R&D: Key reference standard and raw material for research into new topical anti-inflammatory and anti-eczema therapies.
• Psoriasis Treatment: Used in prescription-strength medications to reduce the scaling, itching, and redness associated with plaque psoriasis.
• Eczema and Dermatitis Management: Formulated into products aimed at controlling symptoms of atopic dermatitis, contact dermatitis, and other eczematous conditions.
• Veterinary Pharmaceuticals: Employed in topical preparations for managing inflammatory skin conditions in animals.
• Compounding Pharmacy: Sourced by specialized pharmacies for the preparation of customized topical medication blends.

Basic Information

Product Name	Halometasone
CAS No.	50629-82-8
Molecular Formula	C22H27ClFO5
Molecular Weight	425.90 g/mol
Synonyms	Halometasone Monohydrate; 9-Chloro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione; SQ-18566; CGP-14458; Halog; Sicorten; Adcortyl; Halometasone Topical
EINECS	256-674-1

Quality Control

Our Halometasone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. We provide full traceability and support regulatory documentation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in original packaging and protected from moisture and light exposure to maintain stability and potency.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	NMT 5.0%
Related Substances (HPLC)	Total impurities: NMT 2.0% Any individual impurity: NMT 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	NMT 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.