Description

3-(2-Hydroxyethyl)Adenine is a modified nucleobase derivative of adenine, featuring a hydroxyethyl side chain at the N3 position. This structural modification makes it a valuable intermediate in the synthesis of novel nucleoside analogs and pharmaceutical compounds. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and life science sectors for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of antiviral and anticancer nucleoside prodrugs.
• Biochemical Research: Used as a precursor in studies exploring enzyme inhibition, nucleotide metabolism, and signal transduction pathways.
• Antiviral Agent Development: Serves as a core structure for creating analogs targeting viral polymerases and reverse transcriptases.
• Labeled Compound Synthesis: Intermediate for producing radiolabeled or fluorescently tagged nucleotides for diagnostic and tracking applications.
• Polymer Chemistry: Potential monomer or modifier in the creation of functionalized polymers for biomedical applications.
• Academic & Contract Research: Essential reagent in university and CRO laboratories for medicinal chemistry and molecular biology projects.

Basic Information

Product Name	3-(2-Hydroxyethyl)Adenine
CAS No.	50595-17-0
Molecular Formula	C7H9N5O
Molecular Weight	179.18 g/mol
Synonyms	N3-(2-Hydroxyethyl)adenine; 3-(β-Hydroxyethyl)adenine; 3-HEA; 9H-Purin-6-amine, 3-(2-hydroxyethyl)-; Adenine, N3-(2-hydroxyethyl)-; 3-(2-Hydroxyethyl)-9H-purin-6-amine; 3-Hydroxyethyladenine
EINECS	Contact for details

Quality Control

Our 3-(2-Hydroxyethyl)Adenine is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) documenting batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.