Description

4-Methyl-2-Nitrobenzoyl Chloride is a versatile and reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the 4-methyl-2-nitrobenzoyl moiety into target molecules, enabling the creation of complex chemical architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients, dyes, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a substituted benzoyl group.
• Agrochemical Synthesis: Used in the manufacturing of herbicides, fungicides, and insecticides where its specific substitution pattern imparts desired biological activity.
• Dyestuff and Pigment Production: Serves as a building block for azo dyes and other complex organic pigments, contributing to color fastness and stability.
• Polymer Chemistry: Employed in the creation of specialty monomers and polymers, including polyamides and polyesters with specific functional properties.
• Ligand and Catalyst Development: Useful in the preparation of specialized ligands for metal catalysis and organocatalysts in asymmetric synthesis.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating novel chemical entities.

Basic Information

Item	Details
Product Name	4-Methyl-2-Nitrobenzoyl Chloride
CAS No.	50424-81-2
Molecular Formula	C8H6ClNO3
Molecular Weight	199.59 g/mol
Synonyms	2-Nitro-4-methylbenzoyl chloride; 4-Methyl-2-nitrobenzoic acid chloride; 2-Nitro-p-toluoyl chloride; p-Tolyl-2-nitro ketone chloride; 4-Methyl-2-nitrobenzoylchloride; α-Chloro-4-methyl-2-nitroacetophenone (obsolete); 2-Nitro-4-methylbenzenecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Methyl-2-Nitrobenzoyl Chloride is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for fine chemical synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.