Description

1H-Imidazole-4-Carbonyl Chloride, 2-Amino-4,5-Dihydro- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its reactive carbonyl chloride group, which enables efficient coupling reactions to form amide bonds, making it a critical intermediate for constructing complex molecular architectures. Pharmaceutical and agrochemical R&D teams need this high-purity intermediate for developing novel active ingredients, particularly in medicinal chemistry programs targeting new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry for heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides with specific biological activity.
• Peptide Mimetics & Conjugation: The reactive acid chloride functionality facilitates the creation of peptide analogs and bioconjugates for biochemical research.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialized polymers and functional materials.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for studying biological pathways and enzyme interactions.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Item	Details
Product Name	1H-Imidazole-4-Carbonyl Chloride, 2-Amino-4,5-Dihydro- (9Ci)
CAS No.	50420-34-3
Molecular Formula	C4H4ClN3O
Molecular Weight	145.55 g/mol
Synonyms	2-Amino-4,5-dihydro-1H-imidazole-4-carbonyl chloride; 2-Amino-2-imidazoline-4-carbonyl chloride; 4-(Chlorocarbonyl)-2-amino-4,5-dihydro-1H-imidazole; 2-Amino-4,5-dihydro-1H-imidazole-4-carboxylic acid chloride; 2-Amino-4,5-dihydroimidazole-4-carbonyl chloride; 2-Amino-δ²-imidazoline-4-carbonyl chloride; 1H-Imidazole-4-carbonyl chloride, 2-amino-4,5-dihydro-
EINECS	Contact for details

Quality Control

Our 1H-Imidazole-4-Carbonyl Chloride, 2-Amino-4,5-Dihydro- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.