Description

Diethyl (Isopropyloxycarbonylmethyl)Phosphonate is a high-purity organophosphorus compound, specifically a phosphonate ester, serving as a critical synthetic intermediate. Its primary value lies in its role as a versatile building block for the Horner-Wadsworth-Emmons (HWE) olefination reaction, enabling the efficient synthesis of complex alkenes and other valuable molecules. This product is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality reagents for advanced synthesis.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing olefin linkages in drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators requiring specific alkene functionalities.
• Material Science Precursor: Serves as a building block for functionalized polymers, ligands, and organic electronic materials.
• Organic Synthesis Reagent: A crucial reagent for the Horner-Wadsworth-Emmons reaction, facilitating the formation of carbon-carbon double bonds with high stereoselectivity.
• Flavor & Fragrance Industry: Intermediate in the synthesis of specific aroma chemicals and flavor compounds.
• Research & Development: Used in academic and industrial laboratories for method development and the synthesis of novel organic compounds.

Basic Information

Product Name	Diethyl (Isopropyloxycarbonylmethyl)Phosphonate
CAS No.	50350-99-7
Molecular Formula	C9H19O5P
Molecular Weight	238.22 g/mol
Synonyms	Diethyl (1-isopropoxycarbonyl)methylphosphonate; (Isopropoxycarbonylmethyl)phosphonic Acid Diethyl Ester; Diethyl (isopropoxycarbonyl)methylphosphonate; Diethyl P-(isopropoxycarbonyl)methylphosphonate; Phosphonic acid, P-[(1-isopropoxycarbonyl)methyl]-, diethyl ester; Diethyl (1-isopropoxy-1-oxo-2-propyl)phosphonate; Horner-Wadsworth-Emmons Reagent; HWE Reagent
EINECS	Contact for details

Quality Control

Our Diethyl (Isopropyloxycarbonylmethyl)Phosphonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and moisture. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.