Description

Azidotris(Dimethylamino)Phosphonium Hexafluorophosphate is a specialized organophosphorus reagent primarily used as a highly effective coupling agent in peptide synthesis. Its value lies in its ability to facilitate the formation of amide bonds under mild conditions, offering advantages in yield and purity for complex molecule assembly. This compound is essential for research and development chemists in the pharmaceutical, biotechnology, and advanced materials sectors who require reliable and high-purity reagents for solid-phase and solution-phase synthesis.

Application

• Peptide Coupling Reagent: A key component in the synthesis of peptides and peptidomimetics, enabling efficient amide bond formation.
• Pharmaceutical Intermediate Synthesis: Used in the preparation of active pharmaceutical ingredients (APIs) and complex organic molecules requiring high-fidelity coupling steps.
• Bioconjugation Chemistry: Facilitates the labeling and modification of biomolecules such as proteins and oligonucleotides for diagnostic and therapeutic applications.
• Materials Science Research: Employed in the synthesis of specialized polymers and dendrimers where controlled linkage is critical.
• Academic & Industrial R&D: A valuable tool for chemists exploring new synthetic methodologies in organic and medicinal chemistry.

Basic Information

Product Name	Azidotris(Dimethylamino)Phosphonium Hexafluorophosphate
CAS No.	50281-51-1
Molecular Formula	C6H18N6P•PF6
Molecular Weight	398.19 g/mol
Synonyms	BEMP Azide Hexafluorophosphate Salt; Azidotris(dimethylamino)phosphonium Hexafluorophosphate; Phosphonium, azidotris(dimethylamino)-, hexafluorophosphate(1-); Azido-tris-dimethylamino-phosphonium Hexafluorophosphate; ATMP•HPF6; Coupling Reagent BEMP-Azide; (Dimethylamino)(azido)phosphonium Hexafluorophosphate Derivative
EINECS	Contact for details

Quality Control

Our Azidotris(Dimethylamino)Phosphonium Hexafluorophosphate is manufactured under controlled conditions to ensure high chemical purity and batch-to-batch consistency suitable for demanding synthetic applications. Quality is verified through analytical techniques including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.