Description

Gitoxigenin 3,16-Diacetate is a high-purity, semi-synthetic cardiac glycoside derivative. This compound serves as a critical intermediate in the research and development of novel pharmaceutical agents, particularly in the field of cardiology. It is essential for scientists and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality building blocks for synthesis and biological evaluation.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of cardiac glycosides and related therapeutic compounds.
• Biochemical Research: Used as a reference standard or probe in studies investigating sodium-potassium ATPase (Na+/K+-ATPase) inhibition and cardiac cell signaling pathways.
• Medicinal Chemistry: A versatile scaffold for the structural modification and development of new drug candidates with potential inotropic activity.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis (HPLC, LC-MS).
• Academic Research: Utilized in university and institutional labs for pharmacological and toxicological studies related to heart function.

Basic Information

Product Name	Gitoxigenin 3,16-Diacetate
CAS No.	5996-03-2
Molecular Formula	C30H44O8
Molecular Weight	532.67 g/mol
Synonyms	3β,16β-Diacetoxy-14-hydroxy-5β-card-20(22)-enolide; Gitoxigenin Diacetate; 16-Acetylgitoxin; 3,16-Di-O-acetylgitoxigenin; Strophanthidin-3,16-diacetate; (3β,5β,16β)-3,16-Bis(acetyloxy)-14-hydroxycard-20(22)-enolide; NSC 199742
EINECS	Contact for details

Quality Control

Our Gitoxigenin 3,16-Diacetate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.