Description

2',3'-Dideoxyuridine is a synthetic nucleoside analog that serves as a critical building block and research tool in medicinal chemistry. Its modified sugar moiety makes it a valuable intermediate for the development of antiviral and anticancer nucleotide analogs. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those focused on nucleoside chemistry, prodrug development, and antiviral drug discovery programs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to DNA/RNA metabolism and viral replication.
• Prodrug Development: Serves as a core structure for designing prodrugs with improved bioavailability and targeted delivery.
• Antiviral Agent Synthesis: Fundamental building block for compounds targeting viruses such as HIV, HBV, and herpes viruses.
• Chemical Biology Probes: Utilized in the creation of molecular probes to study cellular processes and drug mechanisms of action.
• Reference Standard: Acts as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	2',3'-Dideoxyuridine
CAS No.	5983-09-5
Molecular Formula	C9H12N2O4
Molecular Weight	212.20 g/mol
Synonyms	2',3'-Dideoxyuridine; ddU; DDU; 1-[(2R,5S)-5-(Hydroxymethyl)-2,5-dihydrofuran-2-yl]pyrimidine-2,4(1H,3H)-dione; 2',3'-Dideoxy-Uridine; Uridine, 2',3'-dideoxy-; NSC 614391; 2',3'-ddU
EINECS	227-795-1

Quality Control

Our 2',3'-Dideoxyuridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.