Description

3-Methoxyestra-1,3,5(10)-Triene-4,17β-Diol CAS NO 5976-66-9 is a high-purity steroid derivative, also known as 4-Hydroxyestradiol 3-Methyl Ether, serving as a critical intermediate in advanced pharmaceutical synthesis. This compound is valued for its defined chemical structure, which is essential for research and development in endocrinology and hormone-related therapies. It is primarily utilized by manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and reference standards.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of steroidal drugs and hormone analogs.
• Biochemical Research: Used as a reference standard or reagent in studies of estrogen metabolism and receptor activity.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules for academic and industrial research.
• Analytical Standard: Serves as a high-purity calibrant in chromatographic analysis (HPLC, GC) for quality control laboratories.
• Development of Diagnostic Kits: Potential use in formulating components for diagnostic assays related to hormonal balance.

Basic Information

Product Name	3-Methoxyestra-1,3,5(10)-Triene-4,17β-Diol
CAS No.	5976-66-9
Molecular Formula	C19H26O3
Molecular Weight	302.41 g/mol
Synonyms	4-Hydroxyestradiol 3-Methyl Ether; 3-Methoxyestra-1,3,5(10)-triene-4,17β-diol; 4,17β-Dihydroxy-3-methoxyestra-1,3,5(10)-triene; 3-Methoxy-4,17β-estradiol; 4-Hydroxy-3-methoxyestra-1,3,5(10)-triene-17β-ol
EINECS	Contact for details

Quality Control

Our 3-Methoxyestra-1,3,5(10)-Triene-4,17β-Diol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D and fine chemical applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.