Description

Proparacaine Hydrochloride is a potent, fast-acting local anesthetic agent belonging to the ester class. Its primary value lies in providing rapid and profound topical anesthesia with a relatively short duration of action, making it ideal for procedures requiring quick onset and recovery. This compound is essential for manufacturers in the ophthalmic pharmaceutical sector, where it is formulated into diagnostic and surgical solutions. It is also utilized in research settings for neuropharmacological studies.

Application

• Ophthalmic Anesthesia: Primary use in topical anesthetic eye drops for tonometry, cataract surgery, and other minor ocular procedures.
• Diagnostic Formulations: Key ingredient in solutions used for corneal anesthesia during eye examinations and contact tonometry.
• Veterinary Medicine: Employed in topical anesthetic preparations for ophthalmic procedures in animals.
• Pharmaceutical Intermediates: Serves as a critical starting material or intermediate in the synthesis of more complex anesthetic agents.
• Research & Development: Used in biochemical and pharmacological research to study sodium channel blockade and local anesthetic mechanisms.

Basic Information

Product Name	Proparacaine Hydrochloride
CAS No.	5875-06-9
Molecular Formula	C16H27ClN2O3
Molecular Weight	330.85 g/mol
Synonyms	Proxymetacaine Hydrochloride; Ophthalme; Alcaine; AK-Taine; Paracaine; 2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate hydrochloride; Benzoic acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl ester, hydrochloride
EINECS	227-525-7

Quality Control

Our Proparacaine Hydrochloride is manufactured and tested to meet high-purity standards suitable for pharmaceutical applications. Quality assurance includes rigorous analytical testing against established pharmacopeial references where applicable. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing purity, identity, and impurity profiles to ensure compliance with your specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	98.0% - 102.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.