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6-Chloropurine Riboside-5'-o-Monophosphate Sodium Salt CAS NO 5843-59-4


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CAS No.:5843-59-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-Chloropurine Riboside-5'-o-Monophosphate Sodium Salt is a key nucleotide analog and biochemical building block essential for research and pharmaceutical development. This compound serves as a critical intermediate in the synthesis of modified nucleosides and nucleotides, enabling advancements in antiviral and anticancer drug discovery. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for developing novel therapeutic agents and conducting biochemical studies.

Application

  • Pharmaceutical Intermediate: Critical building block for the synthesis of antiviral and anticancer nucleoside analogs.
  • Biochemical Research: Used as a substrate or inhibitor in enzymatic studies involving kinases and other nucleotide-processing enzymes.
  • Pro-drug Development: Serves as a monophosphate precursor in the design of nucleotide pro-drugs for improved cellular delivery.
  • Antiviral Agent Synthesis: Key intermediate in the research and production of potential antiviral compounds targeting viral polymerases.
  • Labeled Compound Synthesis: Used as a starting material for preparing isotopically labeled (e.g., 13C, 15N) nucleotides for metabolic tracing studies.
  • Life Science Reagents: Component in the formulation of specialized reagents and kits for molecular biology applications.

Basic Information

Product Name 6-Chloropurine Riboside-5'-o-Monophosphate Sodium Salt
CAS No. 5843-59-4
Molecular Formula C10H11ClN4NaO7P
Molecular Weight 388.63 g/mol
Synonyms 6-Chloropurine Riboside 5'-Monophosphate Sodium Salt; 6-Chloro-9-β-D-ribofuranosylpurine 5'-Monophosphate Sodium Salt; 6-Chloropurine Ribonucleotide Sodium Salt; Sodium 6-Chloro-9-(5-O-phosphono-β-D-ribofuranosyl)purine; 6-Cl-PuR 5'-MP Na Salt; 6-Chloro-9-(5-O-phosphono-β-D-ribofuranosyl)-9H-purine Sodium Salt; 6-Chloropurine Riboside 5'-Phosphate Sodium Salt
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Quality Control

Our 6-Chloropurine Riboside-5'-o-Monophosphate Sodium Salt is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-purity standards suitable for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC/IR) Conforms to reference standard
Assay (HPLC) ≥95.0%
Purity (HPLC, Area%) ≥98.0%
Water Content (KF) ≤5.0%
Heavy Metals ≤20 ppm
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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