Description

Dextrallorphan CAS NO 5822-43-5 is a high-purity pharmaceutical intermediate and research chemical belonging to the morphinan class. This compound is of significant interest for its role in the development and synthesis of advanced therapeutic agents targeting the central nervous system. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in neuropharmacology and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel opioid receptor modulators and antitussive agents.
• Medicinal Chemistry Research: Used as a reference standard and precursor in the study of structure-activity relationships (SAR) for CNS-active compounds.
• Biochemical Research: Employed in receptor binding assays and pharmacological studies to investigate neurological pathways.
• Fine Chemical Synthesis: Serves as a chiral template for the production of specialized, high-value chemical entities.
• Reference Standard: Provides a certified material for analytical method development, validation, and quality control in pharmaceutical analysis.

Basic Information

Product Name	Dextrallorphan
CAS No.	5822-43-5
Molecular Formula	C18H25NO
Molecular Weight	271.40 g/mol
Synonyms	Dextrallorphan; (+)-3-Hydroxy-N-methylmorphinan; Dextromethorphan metabolite; Dextrorphan; (9α,13α,14α)-3-Hydroxy-17-methylmorphinan; Ro 1-5470
EINECS	Contact for details

Quality Control

Our Dextrallorphan is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to confirm identity and potency. A detailed Certificate of Analysis (COA) is provided with each batch, documenting compliance with agreed specifications. We support development and commercial projects requiring standards aligned with GMP and ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.