Description

5α-Cholestane-4β,5-Diol 4-Acetate is a high-purity steroidal intermediate of significant importance in advanced pharmaceutical research and synthesis. This compound serves as a critical building block for the development and production of complex steroid-based active pharmaceutical ingredients (APIs) and reference standards. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in steroid chemistry, metabolic studies, and the synthesis of novel therapeutic agents. The product is supplied with a commitment to stringent quality control to ensure reliability and consistency for sensitive applications.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex steroid hormones and their derivatives.
• Reference Standard: Used as an analytical standard in chromatography (HPLC, GC) for method development, validation, and quality control of related steroid compounds.
• Biochemical Research: Employed in metabolic pathway studies, enzyme inhibition assays, and investigations into cholesterol biosynthesis and related biological processes.
• Fine Chemical Synthesis: Serves as a specialized starting material for custom synthesis and the production of high-value, low-volume steroidal compounds for research markets.

Basic Information

Product Name	5α-Cholestane-4β,5-Diol 4-Acetate
CAS No.	5789-00-4
Molecular Formula	C₂₉H₅₀O₃
Molecular Weight	446.71 g/mol
Synonyms	4β,5-Dihydroxycholestan-4-yl acetate; 5α-Cholestane-4β,5-diol, 4-acetate; (4β,5α)-4-(Acetyloxy)cholestane-5-ol; Cholestane-4β,5-diol 4-acetate; 4-Acetoxy-5α-cholestan-5β-ol
EINECS	Contact for details

Quality Control

Our 5α-Cholestane-4β,5-Diol 4-Acetate is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and synthesis. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to ensure traceability and batch-to-batch consistency for our pharmaceutical sector clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Specific Rotation	Contact for details
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.