Description

N6-Aminoadenosine CAS NO 5746-27-0 is a modified nucleoside derivative of adenosine, featuring an amino group substitution at the N6 position of the adenine base. This structural modification makes it a valuable intermediate and building block in the synthesis of more complex nucleoside analogs and pharmaceutical agents. It is primarily utilized by research institutions and manufacturers in the life sciences sector for developing novel therapeutic compounds and biochemical tools.

Application

• Pharmaceutical Intermediate: A key starting material for the synthesis of novel adenosine receptor agonists, antagonists, and other nucleoside-based drug candidates.
• Biochemical Research: Used as a precursor in enzymatic studies, metabolic pathway analysis, and the investigation of nucleotide-related biological processes.
• Antiviral/Anticancer Agent Development: Serves as a core scaffold for creating potential therapeutic agents targeting viral replication or uncontrolled cell proliferation.
• Labeled Compound Synthesis: Employed in the production of isotopically labeled (e.g., 13C, 15N) nucleosides for use as tracers in mass spectrometry and NMR-based research.
• Enzyme Substrate/Analog: Acts as a substrate or inhibitor for enzymes such as adenosine deaminase, kinases, and methyltransferases in mechanistic studies.
• Oligonucleotide Synthesis: Can be incorporated into oligonucleotide chains to study structure-activity relationships or to create modified aptamers.

Basic Information

Product Name	N6-Aminoadenosine
CAS No.	5746-27-0
Molecular Formula	C10H14N6O4
Molecular Weight	282.26 g/mol
Synonyms	6-Amino-9-β-D-ribofuranosyl-9H-purine; 6-Aminoadenosine; N6-Aminoadenosine; Adenosine, 6-amino-; 9H-Purin-6-amine, 9-β-D-ribofuranosyl-; 6-Amino-9-β-D-ribofuranosylpurine; 6-NH2-Ado
EINECS	227-274-4

Quality Control

Our N6-Aminoadenosine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.