Description

(17α)-12β-Hydroxy-5α-Pregnan-20-One CAS NO 5618-23-5 is a high-purity steroid derivative, specifically a hydroxylated pregnane, serving as a critical intermediate in advanced organic synthesis. This compound matters for its role in the research and development of novel pharmaceutical agents, particularly in the steroid and hormone therapeutic areas. It is needed by R&D laboratories, pharmaceutical manufacturers, and fine chemical synthesis companies focused on producing specialized bioactive molecules and reference standards.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial laboratories for studying steroid metabolism, receptor binding, and structure-activity relationships (SAR).
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis (e.g., HPLC, LC-MS).
• Biochemical Research: Employed in metabolic pathway studies and as a precursor for labeled compounds in tracer experiments.
• Fine Chemical Synthesis: Utilized for the custom synthesis of specialized pregnane derivatives and other steroidal compounds for various applications.

Basic Information

Product Name	(17α)-12β-Hydroxy-5α-Pregnan-20-One
CAS No.	5618-23-5
Molecular Formula	C21H34O2
Molecular Weight	318.50 g/mol
Synonyms	12β-Hydroxy-5α-pregnan-20-one; 12β-Hydroxy-5α-pregnane-20-one; 5α-Pregnan-12β-ol-20-one; 20-Oxo-5α-pregnan-12β-ol; (5α,12β,17α)-12-Hydroxypregnan-20-one; 12β-Hydroxypregnan-20-one; Pregnan-12β-ol-20-one, (5α)-
EINECS	Contact for details

Quality Control

Our (17α)-12β-Hydroxy-5α-Pregnan-20-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥98% by HPLC), identification, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.