Description

12β-Hydroxy-5α-Pregnan-20-One is a high-purity steroid derivative and a key intermediate in organic synthesis. This compound is valued for its defined stereochemistry and structural framework, which serves as a crucial building block for the development of more complex bioactive molecules. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in steroid chemistry, hormone research, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of specialized steroid-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or a starting material in metabolic pathway studies and receptor binding assays.
• Hormone Analog Development: Serves as a core scaffold for the research and development of novel hormone analogs and modulators.
• Organic Synthesis: Employed as a chiral building block in advanced organic chemistry for constructing complex molecular architectures.

Basic Information

Product Name	12β-Hydroxy-5α-Pregnan-20-One
CAS No.	5618-22-4
Molecular Formula	C21H34O2
Molecular Weight	318.50 g/mol
Synonyms	12β-Hydroxy-5α-pregnan-20-one; 5α-Pregnan-12β-ol-20-one; 20-Oxo-5α-pregnan-12β-ol; 12β-Hydroxy-5α-pregnane-20-one; 12β-Hydroxypregnan-20-one; Pregnan-12β-ol-20-one, 5α-; (5α,12β)-Pregnan-20-one-12-ol
EINECS	Contact for details

Quality Control

Our 12β-Hydroxy-5α-Pregnan-20-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by chromatography, to ensure it meets exacting standards for research and synthesis. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.