Description

12β-Acetyloxy-5α-Pregn-16-En-20-One is a high-purity steroid derivative and a key synthetic intermediate in the production of specialized pharmaceutical compounds. Its precise stereochemistry and functional groups make it a valuable building block for researchers and manufacturers developing novel therapeutic agents. This compound is primarily utilized in the pharmaceutical and biotechnology sectors for the synthesis of active pharmaceutical ingredients (APIs) and for advanced research in medicinal chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of steroidal drugs and hormones.
• Medicinal Chemistry Research: Used as a scaffold or starting material for the design and development of new chemical entities with potential biological activity.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the manufacturing process of specific, high-value steroid-based APIs.
• Biochemical Research: Serves as a standard or reference compound in studies involving steroid metabolism and receptor interactions.
• Process Development & Scale-Up: Used in optimizing synthetic routes for the commercial production of complex steroid molecules.

Basic Information

Product Name	12β-Acetyloxy-5α-Pregn-16-En-20-One
CAS No.	5618-21-3
Molecular Formula	C23H34O3
Molecular Weight	358.52 g/mol
Synonyms	12β-Acetoxy-5α-pregn-16-en-20-one; 5α-Pregn-16-en-20-one, 12β-(acetyloxy)-; 12β-Acetoxy-5α-pregna-16,20-dien-3-one (related); 12β-Hydroxy-5α-pregn-16-en-20-one acetate; Pregn-16-ene-20-one, 12β-acetoxy-5α-; 12β-Acetyloxypregna-5,16-dien-20-one (alternative); 12-Acetoxy-5α-pregn-16-en-20-one
EINECS	Contact for details

Quality Control

Our 12β-Acetyloxy-5α-Pregn-16-En-20-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.