Description

4-(4-Nitrophenyl)Butyryl Chloride is a versatile and reactive organic intermediate, specifically an acid chloride derivative of 4-(4-nitrophenyl)butyric acid. Its primary value lies in its role as a key building block for the synthesis of more complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. This compound is essential for researchers and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require a high-purity reagent for amide coupling and esterification reactions.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing amide or ester linkages.
• Peptide Mimetics & Drug Discovery: Used in medicinal chemistry for the preparation of peptide analogs and small molecule libraries for biological screening.
• Agrochemical Synthesis: Employed in the production of advanced crop protection agents and herbicides.
• Liquid Crystal & Polymer Chemistry: Acts as a monomer or modifying agent in the synthesis of specialized polymers and liquid crystal materials.
• Dye & Pigment Manufacturing: Utilized in the synthesis of complex organic dyes and pigments due to the nitro and acyl chloride functional groups.
• Bioconjugation & Probe Synthesis: Facilitates the labeling of biomolecules (proteins, peptides) for diagnostic and research applications.

Basic Information

Item	Details
Product Name	4-(4-Nitrophenyl)Butyryl Chloride
CAS No.	5600-63-5
Molecular Formula	C10H10ClNO3
Molecular Weight	227.65 g/mol
Synonyms	4-(4-Nitrophenyl)butanoyl chloride; p-Nitrophenylbutyryl chloride; 4-(p-Nitrophenyl)butyryl chloride; 4-Nitrophenylbutyroyl chloride; γ-(4-Nitrophenyl)butyryl chloride; 4-(4-Nitro-phenyl)-butyryl chloride; Butanoyl chloride, 4-(4-nitrophenyl)-; 1-(4-Nitrophenyl)-4-chloro-1-butanone (tautomeric form)
EINECS	Contact for details

Quality Control

Our 4-(4-Nitrophenyl)Butyryl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis. We adhere to cGMP principles where applicable. Comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, is performed. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts vigorously with water, alcohols, and bases. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.