Description

Pentagastrin is a synthetic pentapeptide that mimics the biological activity of the C-terminal tetrapeptide of gastrin. It is a critical diagnostic and research agent used to stimulate gastric acid secretion. This compound is essential for pharmaceutical research, clinical diagnostics, and biochemical studies. It serves the needs of pharmaceutical manufacturers, clinical laboratories, and academic research institutions globally.

Application

• Gastric Function Testing: Primarily used as a diagnostic agent in gastric acid secretion tests (e.g., pentagastrin stimulation tests) to assess gastric secretory function and diagnose conditions like Zollinger-Ellison syndrome or atrophic gastritis.
• Pharmacological Research: Employed as a standard tool in preclinical studies to investigate gastrin receptor (CCK2 receptor) activity, signaling pathways, and the development of receptor antagonists.
• Biochemical Standard: Serves as a reference standard in analytical laboratories for method development, validation, and quality control of gastrin-related assays.
• Endocrine Studies: Used in research to study the physiological and pathological roles of gastrin in gastrointestinal health, mucosal growth, and tumor biology.

Basic Information

Product Name	Pentagastrin
CAS No.	5534-95-2
Molecular Formula	C37H49N7O9S
Molecular Weight	767.90 g/mol
Synonyms	N-[(1,1-Dimethylethoxy)carbonyl]-β-alanyl-L-tryptophyl-L-methionyl-L-α-aspartyl-L-phenylalaninamide; N-t-BOC-β-Ala-Trp-Met-Asp-Phe-NH2; BOC-β-Ala-Trp-Met-Asp-Phe-NH2; Gastrin Pentapeptide; Peptavlon (brand name); AY-6608; ICI-50,123; Pentagastrin Acetate
EINECS	226-882-5

Quality Control

Our Pentagastrin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and tests for related substances and residual solvents. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and diagnostic-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.5%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.