Description

Dichloro(p-Fluorophenyl)Phosphine is a versatile organophosphorus compound that serves as a critical building block in advanced chemical synthesis. Its value lies in its bifunctional reactivity, featuring both a phosphorus-halogen bond and an aromatic fluorine substituent, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors who require high-purity intermediates for ligand synthesis and catalyst development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Ligand Synthesis: Used to manufacture sophisticated phosphine ligands for homogeneous catalysis in fine chemical production.
• Agrochemical Development: Building block for creating new generation herbicides, fungicides, and plant growth regulators.
• Material Science: Intermediate in the production of flame retardants, stabilizers, and specialty polymers.
• Cross-Coupling Catalysis: Serves as a precursor for catalysts used in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions.
• Organic Synthesis Research: Valuable reagent for academic and industrial R&D in constructing complex organophosphorus molecules.

Basic Information

Product Name	Dichloro(p-Fluorophenyl)Phosphine
CAS No.	5510-93-0
Molecular Formula	C6H4Cl2FP
Molecular Weight	196.97 g/mol
Synonyms	(p-Fluorophenyl)dichlorophosphine; (4-Fluorophenyl)dichlorophosphine; 4-Fluorophenyldichlorophosphine; Dichloro(4-fluorophenyl)phosphine; p-Fluorophenyldichlorophosphine; 1-Fluoro-4-(dichlorophosphino)benzene; Phosphonous dichloride, P-(4-fluorophenyl)-
EINECS	226-847-9

Quality Control

Our Dichloro(p-Fluorophenyl)Phosphine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic and spectroscopic methods, to verify identity and purity. Certificates of Analysis (COA) detailing all test results are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 15-25°C. Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (argon or nitrogen) to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong oxidizers, bases, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.