Description

1,3,7-Trimethyl-8-Methylamino-Purine-2,6-Dione is a high-purity xanthine derivative, also known as 8-Methylaminotheophylline, with significant biological activity. This compound is valued for its role as a key intermediate and reference standard in advanced pharmaceutical research and development. It is primarily required by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly in the fields of cardiology and respiratory medicine.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of specialized xanthine-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and tool compound in studies investigating adenosine receptor antagonism and phosphodiesterase (PDE) inhibition.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for quality control and method validation in analytical laboratories.
• Life Science Reagent: Employed in cell-based assays and pharmacological screening to study cardiovascular and pulmonary pathways.

Basic Information

Product Name	1,3,7-Trimethyl-8-Methylamino-Purine-2,6-Dione
CAS No.	5422-30-0
Molecular Formula	C9H13N5O2
Molecular Weight	223.23 g/mol
Synonyms	8-Methylaminotheophylline; 8-(Methylamino)theophylline; 1,3,7-Trimethyl-8-(methylamino)-3,7-dihydro-1H-purine-2,6-dione; 8-Methylamino-1,3,7-trimethylxanthine; 8-Methylaminotheophylline; 8-MAT; 8-Methylamino-3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
EINECS	Contact for details

Quality Control

Our 1,3,7-Trimethyl-8-Methylamino-Purine-2,6-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.