Description

6-Chloropurine Riboside is a key nucleoside analog and versatile biochemical building block. This compound is essential for research and development in medicinal chemistry, serving as a crucial precursor for the synthesis of various antiviral and anticancer agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on nucleoside-based therapeutics.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of antiviral drugs (e.g., certain adenosine analogs) and potential anticancer compounds.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving purine metabolism and nucleoside kinases.
• Medicinal Chemistry: Serves as a scaffold for structure-activity relationship (SAR) studies and the development of novel nucleoside derivatives.
• Antiviral Agent Development: Investigated for its role in creating analogs that interfere with viral RNA/DNA synthesis.
• Labeled Compound Synthesis: Starting material for the preparation of radiolabeled or isotopically labeled nucleosides for tracer studies.
• Library Synthesis: Building block for combinatorial chemistry libraries targeting purinergic receptors.

Basic Information

Product Name	6-Chloropurine Riboside
CAS No.	5399-87-1
Molecular Formula	C10H11ClN4O4
Molecular Weight	286.67 g/mol
Synonyms	6-Chloro-9-β-D-ribofuranosylpurine; 6-Chloropurine-9-riboside; 6-Chloro-9-(β-D-ribofuranosyl)purine; 6-Chloropurine Ribonucleoside; 6-Chloro-9-ribosylpurine; NSC 74964; 6-Cl-Purine Riboside
EINECS	226-404-8

Quality Control

Our 6-Chloropurine Riboside is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and synthesis applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to current industry standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.