Description

Diphenyl Phosphorochloridite is a versatile organophosphorus reagent primarily used as a key intermediate in the synthesis of complex molecules. Its high reactivity makes it invaluable for constructing phosphorus-containing compounds and as a chlorinating agent in specialized organic transformations. This product is essential for research and production in the pharmaceutical, agrochemical, and material science industries, where precise chemical building blocks are required.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), particularly those containing phosphonate or phosphate ester groups.
• Agrochemical Synthesis: Used in the production of pesticides, herbicides, and plant growth regulators that incorporate phosphorus chemistry.
• Ligand and Catalyst Preparation: Serves as a precursor for phosphite and phosphonite ligands used in asymmetric catalysis and transition metal complexes.
• Polymer Modification: Employed in the synthesis of flame retardants, stabilizers, and specialty monomers for high-performance polymers.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and organophosphorus chemistry.
• Nucleotide Chemistry: Used in the controlled synthesis and modification of nucleotides and oligonucleotide analogs.

Basic Information

Product Name	Diphenyl Phosphorochloridite
CAS No.	5382-00-3
Molecular Formula	C12H10ClOP
Molecular Weight	236.63 g/mol
Synonyms	Chlorodiphenoxyphosphine; Diphenoxyphosphinous Chloride; Phenyl Phosphorodichloridite; Phosphorochloridic Acid, Diphenyl Ester; (Diphenoxyphosphoryl)chloride; NSC 404058; Chlorophosphonic Acid Diphenyl Ester
EINECS	226-356-7

Quality Control

Our Diphenyl Phosphorochloridite is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including assay, purity profiling, and identification, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC or Titration)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.