Description

2,2-Dichlorocyclopropanecarbonyl Chloride is a highly reactive bifunctional organochlorine compound that serves as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity of both the acid chloride and the geminal dichlorocyclopropane moieties, enabling the construction of complex molecular architectures. This intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of cyclopropane-containing drug candidates, such as protease inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Building block for creating novel pesticides and herbicides featuring the stable, sterically defined cyclopropane ring.
• Polymer Chemistry: Monomer or cross-linking agent for producing specialty polymers with tailored thermal and chemical resistance properties.
• Ligand and Catalyst Development: Starting material for synthesizing chiral cyclopropane-based ligands used in asymmetric catalysis.
• Material Science Research: Used in the development of advanced organic materials and liquid crystals.
• Custom Synthesis and R&D: A versatile reagent for contract research organizations and academic laboratories exploring new synthetic methodologies.

Basic Information

Product Name	2,2-Dichlorocyclopropanecarbonyl Chloride
CAS No.	5365-15-1
Molecular Formula	C4H3Cl3O
Molecular Weight	173.42 g/mol
Synonyms	2,2-Dichlorocyclopropanecarbonyl chloride; Cyclopropanecarbonyl chloride, 2,2-dichloro-; 2,2-Dichlorocyclopropanecarboxylic acid chloride; 2,2-Dichlorocyclopropanecarboxyl chloride; 2,2-Dichloro-1-cyclopropanecarbonyl chloride; 5365-15-1; Dichlorocyclopropanecarbonyl chloride
EINECS	226-357-9

Quality Control

Every batch of 2,2-Dichlorocyclopropanecarbonyl Chloride is manufactured and tested under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and consistency for your critical synthesis workflows. A detailed Certificate of Analysis (COA), confirming identity, purity, and impurity profiles via techniques such as GC, HPLC, and NMR, is supplied with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and moisture-sensitive nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.