Description

2-(1,3-Dioxoisoindolin-2-Yl)Propanoyl Chloride is a versatile and highly reactive acyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its ability to efficiently introduce the phthalimide-protected amino acid moiety, enabling the synthesis of complex molecules with high precision. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of peptide mimetics and prodrugs, especially those requiring a phthaloyl (Pht) protecting group.
• Agrochemical Synthesis: Used in the creation of novel herbicides and fungicides that incorporate specific amino acid-like structures for targeted activity.
• Polymer Chemistry: Acts as a monomer or modifying agent for producing specialty polyamides and polyimides with tailored properties.
• Bioconjugation: Useful for labeling biomolecules (e.g., proteins, peptides) due to its reactive acid chloride group, facilitating the attachment of reporter groups.
• Material Science Research: Employed in the development of advanced organic materials, including liquid crystals and organic semiconductors.
• Custom Synthesis & Contract Manufacturing: A vital reagent for fine chemical and custom synthesis houses serving the life sciences sector.

Basic Information

Item	Details
Product Name	2-(1,3-Dioxoisoindolin-2-Yl)Propanoyl Chloride
CAS No.	5364-22-7
Molecular Formula	C11H8ClNO3
Molecular Weight	237.64 g/mol
Synonyms	2-(1,3-Dioxoisoindolin-2-yl)propanoyl chloride; 2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoyl chloride; N-Phthaloyl-alanyl chloride; Phthalimidopropionyl chloride; 2-(Phthalimido)propionyl chloride; α-Phthalimidopropionyl chloride; 2-(1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl)propanoyl chloride; NSC 334719
EINECS	Contact for details

Quality Control

Every batch of 2-(1,3-Dioxoisoindolin-2-Yl)Propanoyl Chloride is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemicals and pharmaceutical intermediates. Comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and quality assurance for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.