Description

9,13-Retinoic Acid is a specific geometric isomer of retinoic acid, a key derivative of Vitamin A. This compound is valued for its role as a reference standard and a critical intermediate in the research and synthesis of retinoids, which are pivotal in cellular signaling and differentiation processes. It is primarily sought by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced chemical synthesis sectors for developing therapeutic agents and studying biological pathways.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of retinoid compounds in method development and quality control laboratories.
• Biochemical Research: Serves as a crucial tool in studying retinoic acid receptor (RAR) signaling, gene expression, and cellular differentiation mechanisms.
• Active Pharmaceutical Ingredient (API) Intermediate: Acts as a key synthetic building block in the production of novel retinoid-based therapeutics targeting dermatological and oncological conditions.
• Cosmeceutical R&D: Investigated for potential applications in advanced skincare formulations aimed at modulating skin cell renewal and addressing photoaging.
• Analytical Chemistry: Employed as a high-purity calibrant in chromatographic systems (HPLC, LC-MS) for accurate compound identification and quantification.

Basic Information

Product Name	9,13-Retinoic Acid
CAS No.	5352-74-9
Molecular Formula	C20H28O2
Molecular Weight	300.44 g/mol
Synonyms	(9Z,13Z)-Retinoic Acid; (9Z,13Z)-Retinoate; all-trans-9,13-Di-cis-Retinoic Acid; Vitamin A Acid Isomer; 9,13-Di-cis-Retinoic Acid; Retinoids Intermediate; Tretinoin Isomer
EINECS	226-310-3

Quality Control

We supply 9,13-Retinoic Acid manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) or refrigerated (2-8°C) for long-term stability. The container should be kept in a cool, dry, and well-ventilated area away from oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.