Description

Ethyl 2-Thiocyanatoacetate is a versatile sulfur-containing ester building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a thiocyanate and an ester functional group, makes it a valuable precursor for constructing heterocyclic compounds and other complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel heterocyclic scaffolds with potential biological activity.
• Agrochemical Synthesis: Used as a precursor for developing new pesticides and herbicides, leveraging the reactivity of the thiocyanate group.
• Organic Synthesis Reagent: Serves as a versatile reagent for introducing sulfur and nitrogen-containing functionalities into target molecules.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reaction pathways and creating specialized chemical libraries.
• Ligand and Catalyst Precursor: Can be utilized in the preparation of specialized ligands for metal catalysis.
• Material Science Applications: Potential use in the synthesis of monomers or additives for specialized polymers.

Basic Information

Product Name	Ethyl 2-Thiocyanatoacetate
CAS No.	5349-28-0
Molecular Formula	C5H7NO2S
Molecular Weight	145.18 g/mol
Synonyms	Ethyl thiocyanatoacetate; Acetic acid, 2-thiocyanato-, ethyl ester; Ethyl (thiocyanato)acetate; 2-Thiocyanatoacetic acid ethyl ester; NSC 401119; Thiocyanatoacetic acid ethyl ester; Ethyl 2-isothiocyanatoacetate (common misnomer); Ethyl ester of thiocyanatoacetic acid
EINECS	226-304-1

Quality Control

Our Ethyl 2-Thiocyanatoacetate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with key parameters such as assay (by GC or HPLC), identity confirmation (by IR), and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability, although the product may be stable at controlled room temperature for shorter periods. Keep container tightly sealed when not in use to minimize moisture uptake and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 3.0%
Refractive Index (n20D)	1.470 - 1.480
Density (g/mL at 20°C)	1.150 - 1.180

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.