Description

11Beta,21-Dihydroxypregna-4,17(20)-Dien-3-One 21-Acetate is a high-purity steroid intermediate of significant importance in pharmaceutical synthesis. This compound serves as a critical building block for the development of advanced corticosteroid and other steroidal active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for process development and scale-up production.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent corticosteroid drugs and other therapeutic steroid molecules.
• Research & Development: Used in academic and industrial laboratories for investigating novel synthetic pathways and structure-activity relationships (SAR) of steroidal compounds.
• Process Chemistry: Employed in the development and optimization of scalable manufacturing processes for steroidal APIs under Good Manufacturing Practice (GMP) conditions.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Item	Detail
Product Name	11Beta,21-Dihydroxypregna-4,17(20)-Dien-3-One 21-Acetate
CAS No.	5327-59-3
Molecular Formula	C23H30O5
Molecular Weight	386.48 g/mol
Synonyms	11β,21-Dihydroxypregna-4,17(20)-dien-3-one 21-acetate; 21-Acetoxy-11β,21-dihydroxypregna-4,17(20)-dien-3-one; Pregna-4,17(20)-dien-3-one, 11,21-dihydroxy-, 21-acetate, (11β)-; 11β-Hydroxy-21-acetoxypregna-4,17(20)-dien-3-one
EINECS	Contact for details

Quality Control

Our 11Beta,21-Dihydroxypregna-4,17(20)-Dien-3-One 21-Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediates. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.