Description

1,3-Benzenedicarbonyl Difluoride (9Ci) is a high-purity, reactive aromatic difluoride building block. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, enabling the efficient introduction of the isophthaloyl moiety under mild conditions. It is primarily sought by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of protease inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring isophthalic acid derivatives.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the production of high-performance polyamides, polyesters, and polyimides for engineering plastics and fibers.
• Liquid Crystal & OLED Materials: A crucial precursor in the manufacture of aromatic cores for liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Metal-Organic Frameworks (MOFs): Employed as an organic linker in the construction of porous MOF materials for gas storage, separation, and catalysis.
• Peptide Mimetics & Bioconjugation: Facilitates the creation of peptide analogs and bioconjugation linkers due to its reactivity with nucleophiles like amines and alcohols.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of specialized azo and anthraquinone-based dyes and pigments.
• Academic & Industrial R&D: A valuable reagent for methodological development in fluorination chemistry and cross-coupling reactions.

Basic Information

Product Name	1,3-Benzenedicarbonyl Difluoride (9Ci)
CAS No.	5310-45-2
Molecular Formula	C8H4F2O2
Molecular Weight	170.11 g/mol
Synonyms	Isophthaloyl Difluoride; Isophthalic Acid Difluoride; 1,3-Difluorocarbonylbenzene; Benzene-1,3-dicarbonyl Difluoride; m-Phthaloyl Difluoride; Isophthaloyl Fluoride; m-Difluorocarbonylbenzene; 1,3-Bis(fluorocarbonyl)benzene
EINECS	226-143-8

Quality Control

Our 1,3-Benzenedicarbonyl Difluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and consistency, meeting the stringent requirements for fine chemical synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	64 - 68 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.