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1-(2'-O,3'-o-Cyclopentyl-5'-Hydroxy-β-D-Erythro-Pentofuranosyl)Uracil CAS NO 5297-71-2


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CAS No.:5297-71-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-(2'-O,3'-o-Cyclopentyl-5'-Hydroxy-β-D-Erythro-Pentofuranosyl)Uracil is a sophisticated nucleoside analogue with a modified pentofuranosyl sugar moiety. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its potential as a building block in novel therapeutic agents. It serves as a critical intermediate for researchers and manufacturers in the fields of antiviral drug discovery and oncology research, where precise molecular modifications are key to developing targeted treatments.

Application

  • Pharmaceutical Intermediate: A key synthetic precursor in the development of novel nucleoside-based antiviral medications.
  • Antiviral Research: Investigated for its potential activity against a range of viral pathogens by acting as a nucleoside analogue.
  • Oncological Agent Development: Used in research for creating prodrugs or active metabolites targeting cancer cell proliferation.
  • Biochemical Tool Compound: Employed in enzymatic studies to understand substrate specificity and inhibition mechanisms.
  • Medicinal Chemistry: Serves as a scaffold for structure-activity relationship (SAR) studies to optimize pharmacokinetic properties.
  • Academic & Institutional Research: Utilized in university and institutional labs for fundamental studies in nucleic acid chemistry and drug design.

Basic Information

Product Name 1-(2'-O,3'-o-Cyclopentyl-5'-Hydroxy-β-D-Erythro-Pentofuranosyl)Uracil
CAS No. 5297-71-2
Molecular Formula C₁₄H₂₀N₂O₇
Molecular Weight 328.32 g/mol
Synonyms 1-[2-O,3-O-Cyclopentyl-5-hydroxy-β-D-erythro-pentofuranosyl]uracil; 2'-O,3'-O-Cyclopentyluridine; 5'-Hydroxy-2',3'-O-cyclopentyluridine; Cyclopentyl uridine derivative; Uracil, 1-(2-O,3-O-cyclopentyl-5-hydroxy-β-D-erythro-pentofuranosyl)-; Modified Uridine; Nucleoside Analogue
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Quality Control

Our 1-(2'-O,3'-o-Cyclopentyl-5'-Hydroxy-β-D-Erythro-Pentofuranosyl)Uracil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 2.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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