Description

Guanine 7-Oxide is a purine derivative and an important oxidized form of guanine. This compound is significant in biochemical research, particularly for studying oxidative stress, DNA damage, and nucleotide metabolism. It serves as a critical reference standard and intermediate for researchers and manufacturers in the pharmaceutical, diagnostic, and life science sectors.

Application

• Biochemical Research Standard: Used as a high-purity reference material for the study of oxidative DNA damage and repair mechanisms.
• Pharmaceutical Intermediate: Acts as a key synthetic building block in the development of novel nucleoside analogs and antiviral or anticancer agents.
• Diagnostic Reagent Manufacturing: Employed in the production of reagents and kits for detecting oxidative stress biomarkers in clinical and research settings.
• Metabolic Pathway Studies: Utilized in enzymatic and metabolic studies to understand purine catabolism and the role of oxidized purines.
• Analytical Chemistry: Serves as a calibration standard in advanced analytical techniques such as HPLC-MS and LC-MS/MS for accurate quantification.

Basic Information

Product Name	Guanine 7-Oxide
CAS No.	5227-68-9
Molecular Formula	C5H5N5O2
Molecular Weight	167.13 g/mol
Synonyms	7-Oxoguanine; Guan-7-oxide; 2-Amino-7,9-dihydro-1H-purin-6-one 7-oxide; 2-Amino-6,8-dihydroxypurine; 2-Aminohypoxanthine 7-oxide; 7-Hydroxyguanine; GO
EINECS	226-038-9

Quality Control

Our Guanine 7-Oxide is produced and tested under strict quality management systems. We provide material that meets high-purity standards suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles by HPLC is supplied with each batch to ensure traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.