Description

3,7,12-Trihydroxycholest-24-Enoic Acid is a hydroxylated bile acid derivative with a specific cholestane backbone. This compound matters as a key intermediate and reference standard in the research and development of pharmaceuticals targeting metabolic and liver-related pathways. It is primarily needed by research institutions, pharmaceutical developers, and fine chemical manufacturers focused on hepatology, lipid metabolism, and the synthesis of more complex steroid-based molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel therapeutic agents and more complex bile acid analogs.
• Biochemical Research: Used as a reference standard or substrate in studies of bile acid metabolism, liver function, and cholesterol homeostasis.
• Metabolic Pathway Analysis: Employed in in vitro and in vivo research to investigate the role of specific bile acid derivatives in cellular signaling.
• Analytical Standard: Provides a high-purity standard for quality control and method development in analytical laboratories using techniques like HPLC and LC-MS.
• Enzymology Studies: Acts as a potential substrate or inhibitor for enzymes involved in steroid and bile acid biosynthesis and modification.

Basic Information

Item	Details
Product Name	3,7,12-Trihydroxycholest-24-Enoic Acid
CAS No.	5226-26-6
Molecular Formula	C₂₇H₄₄O₅
Molecular Weight	448.64 g/mol
Synonyms	3α,7α,12α-Trihydroxy-5β-cholest-24-en-26-oic Acid; 3,7,12-Trihydroxy-5β-cholest-24-en-26-oic Acid; 5β-Cholest-24-ene-3α,7α,12α-triol-26-oic Acid; Trihydroxycholestenoic Acid; (24E)-3α,7α,12α-Trihydroxy-5β-cholest-24-en-26-oic Acid
EINECS	Contact for details

Quality Control

Our 3,7,12-Trihydroxycholest-24-Enoic Acid is produced and handled under a strict quality management system. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.