Description

6α-Hydroxy-5β-Androstane-3,17-Dione is a high-purity steroid intermediate of significant importance in advanced pharmaceutical synthesis and biochemical research. This compound serves as a critical building block for the development of novel therapeutic agents and is essential for studying metabolic pathways and enzyme interactions. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in steroid chemistry and endocrinology research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of specialized steroid-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or substrate in metabolic studies, enzyme inhibition assays, and receptor binding experiments.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex molecules for medicinal chemistry and drug discovery programs.
• Metabolite Standard: Serves as an analytical standard for the identification and quantification of steroid metabolites in biological samples.
• Endocrinology Studies: Utilized in research focused on androgen metabolism and the biosynthesis of related hormones.

Basic Information

Product Name	6α-Hydroxy-5β-Androstane-3,17-Dione
CAS No.	5225-43-4
Molecular Formula	C19H28O3
Molecular Weight	304.43 g/mol
Synonyms	6α-Hydroxyetiocholane-3,17-dione; 6α-Hydroxy-5β-androstane-3,17-dione; 5β-Androstane-6α-ol-3,17-dione; 3,17-Dioxo-5β-androstan-6α-ol; 6α-Hydroxy-5β-etiocholane-3,17-dione; NSC 113986
EINECS	Contact for details

Quality Control

Our 6α-Hydroxy-5β-Androstane-3,17-Dione is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and related substance profiling, to meet exacting research and development standards. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.