Description

5'-Deoxyguanosine is a modified nucleoside where the 5'-hydroxyl group of the ribose sugar is replaced by a hydrogen atom. This structural modification makes it a valuable biochemical building block and research tool for studying nucleic acid metabolism and enzyme mechanisms. It is primarily utilized in pharmaceutical research, diagnostic development, and as a key intermediate in the synthesis of nucleotide analogs. Our supply of 5'-Deoxyguanosine CAS NO 5151-99-5 is characterized by high purity and batch-to-batch consistency to meet rigorous research and production standards.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antiviral and anticancer nucleotide analog drugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for nucleoside kinases and phosphorylases.
• Diagnostic Reagent Manufacturing: Serves as a raw material for producing labeled probes and components in diagnostic kits.
• Antisense Oligonucleotide Development: Incorporated into oligonucleotide sequences to modify stability and binding properties.
• Academic & Life Science Research: Fundamental tool for investigating DNA repair mechanisms, metabolic pathways, and cellular signaling.
• Reference Standard: Employed as a high-purity standard for analytical method development and quality control in laboratories.

Basic Information

Product Name	5'-Deoxyguanosine
CAS No.	5151-99-5
Molecular Formula	C10H13N5O4
Molecular Weight	267.24 g/mol
Synonyms	2'-Deoxyguanosine (common misnomer); 5'-dG; 9-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,9-dihydro-6H-purin-6-one; Guanine deoxyriboside; Deoxyguanosine (ambiguous, typically refers to 2'-deoxy); 1-(2-Deoxy-β-D-erythro-pentofuranosyl)guanine
EINECS	225-907-6

Quality Control

Every batch of our 5'-Deoxyguanosine is manufactured and tested under a strict quality management system. We provide comprehensive analytical documentation to ensure the product meets the specific requirements of research and production applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality protocols are designed to support compliance with cGMP and ISO standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Total impurities ≤2.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.