Description

1,3,5[10]-Estratriene-3,16Alpha,17Beta-Triol 3-Sulfate Sodium Salt is a chemically modified, water-soluble derivative of estriol, a naturally occurring estrogen. This compound is valued for its enhanced stability and bioavailability in aqueous formulations compared to its parent hormone. It is primarily utilized in advanced pharmaceutical research and development, particularly for creating reference standards and investigating hormone-related therapeutic pathways.

Application

• Pharmaceutical Reference Standard: Serves as a high-purity calibrant for analytical methods (HPLC, LC-MS) in quality control laboratories.
• Endocrinology Research: Used in biochemical studies to investigate estrogen metabolism, receptor interactions, and sulfate conjugation pathways.
• Drug Discovery & Development: Acts as a key intermediate or metabolite analog in the development of novel hormone therapies and diagnostics.
• Clinical Diagnostics: Employed in the development and calibration of immunoassays for precise measurement of estrogen metabolites in biological samples.
• Biochemical Reagent: Used in enzymatic studies related to steroid sulfatases and sulfotransferases.

Basic Information

Product Name	1,3,5[10]-Estratriene-3,16Alpha,17Beta-Triol 3-Sulfate Sodium Salt
CAS No.	5150-64-1
Molecular Formula	C18H23NaO7S
Molecular Weight	406.42 g/mol
Synonyms	Estriol 3-Sulfate Sodium Salt; Sodium Estriol Sulfate; Estratriol 3-Sulfate Sodium Salt; 16α,17β-Estriol 3-Sulfate Sodium Salt; NSC 147998; 3-Hydroxyestra-1,3,5(10)-triene-16α,17β-diol 3-Sulfate Sodium Salt; Estriol 3-Monosulfate Sodium Salt
EINECS	225-904-4

Quality Control

Our 1,3,5[10]-Estratriene-3,16Alpha,17Beta-Triol 3-Sulfate Sodium Salt is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets stringent specifications for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.