Description

1-(2'-Deoxy-β-D-Glucopyranosyl)Thymine is a nucleoside analog, specifically a thymidine derivative where the deoxyribose sugar is replaced by a 2'-deoxyglucopyranosyl moiety. This structural modification makes it a valuable intermediate and building block in synthetic organic chemistry and pharmaceutical research. It is primarily utilized by researchers and manufacturers in the life sciences sector for developing novel therapeutic agents and biochemical probes. The compound's unique sugar backbone is of significant interest in the study of nucleoside metabolism and the design of antiviral or anticancer prodrugs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleoside metabolism and DNA synthesis pathways.
• Prodrug Development: Serves as a precursor in the design of targeted prodrugs, leveraging its modified sugar for improved bioavailability or tissue specificity.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Chemical Biology: Integral for synthesizing labeled compounds or probes used to study cellular processes and drug-target interactions.
• Academic & Industrial R&D: Fundamental material for exploratory research in medicinal chemistry and glycoscience.

Basic Information

Product Name	1-(2'-Deoxy-β-D-Glucopyranosyl)Thymine
CAS No.	5116-45-0
Molecular Formula	C₁₆H₂₄N₂O₈
Molecular Weight	372.37 g/mol
Synonyms	Thymine 1-(2-deoxy-β-D-glucopyranoside); 1-(2-Deoxy-β-D-glucopyranosyl)thymine; 2'-Deoxy-β-D-glucosylthymine; 5-Methyl-1-(2-deoxy-β-D-glucopyranosyl)uracil; β-Thymidine glucoside; dT-Glc; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1-(2'-Deoxy-β-D-Glucopyranosyl)Thymine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. Certificates of Analysis (COA) documenting all critical quality attributes are provided to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.