Description

4-Oxo-4H-1-Benzopyran-2-Carbonyl Chloride is a versatile and highly reactive organic intermediate, serving as a crucial building block for the synthesis of complex heterocyclic compounds. Its core value lies in its ability to efficiently introduce the chromone-2-carbonyl moiety, enabling the creation of novel molecules with targeted biological and functional properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who are developing new active ingredients, dyes, and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of chromone and flavone derivatives, which are core scaffolds for drugs with anti-inflammatory, anticancer, and antimicrobial activities.
• Agrochemical Synthesis: Used to construct active ingredients for pesticides and herbicides, leveraging the bioactivity of the chromone structure.
• Dye and Pigment Manufacturing: Serves as a starting material for producing organic dyes, fluorescent markers, and photostable pigments.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers with specific optical or electronic properties.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules to study biological processes and interactions.
• Academic & R&D: A fundamental reagent for synthetic organic chemistry research, enabling novel reaction pathways and compound libraries.

Basic Information

Product Name	4-Oxo-4H-1-Benzopyran-2-Carbonyl Chloride
CAS No.	5112-47-0
Molecular Formula	C10H5ClO3
Molecular Weight	208.60 g/mol
Synonyms	Chromone-2-carbonyl chloride; 2-Chlorocarbonylchromone; 2-Chromonecarbonyl chloride; 1-Benzopyran-2-carbonyl chloride, 4-oxo-; 4-Oxo-4H-chromene-2-carbonyl chloride; 4-Oxo-4H-1-benzopyran-2-carboxylic acid chloride; 2-Chlorocarbonyl-4H-chromen-4-one
EINECS	225-828-5

Quality Control

Our 4-Oxo-4H-1-Benzopyran-2-Carbonyl Chloride is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to verify identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters. We adhere to cGMP standards where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.