Description

6-Chloro-3,4-Dihydro-1(2H)-Pyridinecarbonyl Chloride is a versatile and highly reactive bifunctional organic intermediate, serving as a critical building block in advanced chemical synthesis. Its value lies in its ability to introduce both a reactive acid chloride group and a functionalized pyridine moiety into target molecules, enabling the construction of complex heterocyclic systems. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of piperidine and pyridine-based drug candidates, including potential central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require a chlorinated pyridine scaffold for enhanced bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Employed in the synthesis of functional monomers and polymers with specific thermal or electronic properties.
• Material Science Research: Utilized in the development of organic semiconductors, liquid crystals, and other advanced functional materials.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Details
Product Name	6-Chloro-3,4-Dihydro-1(2H)-Pyridinecarbonyl Chloride
CAS No.	5100-15-2
Molecular Formula	C7H7Cl2NO
Molecular Weight	192.04 g/mol
Synonyms	6-Chloro-3,4-dihydro-2H-pyridine-1-carbonyl chloride; 6-Chloro-1,2,3,4-tetrahydropyridine-1-carbonyl chloride; 6-Chloro-1-piperidinecarbonyl chloride; 6-Chloropiperidine-1-carbonyl chloride; 6-Chloro-1,2,3,4-tetrahydropyridine-1-carboxylic acid chloride; 5100-15-2; 6-Chloro-3,4-dihydro-1(2H)-pyridinecarboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 6-Chloro-3,4-Dihydro-1(2H)-Pyridinecarbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and degradation. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.