Description

1H-Pyrrole-1-Carbonyl Chloride, 2-Chloro-4,5-Dihydro- (9Ci) is a reactive heterocyclic acid chloride derivative, serving as a versatile and critical building block in advanced organic synthesis. Its value lies in enabling the efficient introduction of the 2-chloro-4,5-dihydropyrrole-1-carbonyl moiety, a key structural motif for developing novel compounds with targeted biological activities. This high-purity intermediate is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to create new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in developing protease inhibitors, kinase inhibitors, and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, contributing to new modes of action.
• Material Science Research: Employed in the development of specialty polymers, ligands, and functional materials that incorporate the pyrrole heterocycle.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling, cross-linking, or modifying biomolecules in probe development.
• Academic & R&D Laboratories: Serves as a fundamental reagent for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	1H-Pyrrole-1-Carbonyl Chloride, 2-Chloro-4,5-Dihydro- (9Ci)
CAS No.	5100-13-0
Molecular Formula	C5H5Cl2NO
Molecular Weight	166.00 g/mol
Synonyms	2-Chloro-4,5-dihydro-1H-pyrrole-1-carbonyl chloride; 2-Chloro-2,3-dihydro-1H-pyrrole-1-carbonyl chloride; 1-Carbonylchloride-2-chloro-4,5-dihydropyrrole; 2-Chloro-1-pyrroline-1-carbonyl chloride; 2-Chloro-δ1-pyrroline-1-carbonyl chloride; 2-Chloro-2,5-dihydro-1H-pyrrole-1-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 1H-Pyrrole-1-Carbonyl Chloride, 2-Chloro-4,5-Dihydro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request, providing full traceability and compliance assurance for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, it should be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.