Description

Cytidine, 2'-Deoxy-3-Methyl- CAS NO 5040-21-1 is a modified nucleoside derivative, specifically a methylated analog of deoxycytidine. This compound is of significant interest in biochemical research and pharmaceutical development due to its role as a building block for oligonucleotide synthesis and its potential as a metabolic intermediate. It is primarily utilized by researchers and manufacturers in the fields of nucleic acid chemistry, antiviral drug discovery, and molecular biology.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel antiviral and anticancer nucleoside analogs.
• Oligonucleotide Synthesis: Used as a modified building block (phosphoramidite) for the solid-phase synthesis of DNA and RNA strands with specific methylation patterns for epigenetic studies.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies involving DNA methyltransferases and other nucleic acid-modifying enzymes.
• Metabolite Standard: Acts as a reference standard in analytical methods such as HPLC and LC-MS for the detection and quantification of nucleoside metabolites in biological samples.
• Life Science Reagents: Incorporated into specialized cell culture media or diagnostic assay kits for targeted research applications.

Basic Information

Product Name	Cytidine, 2'-Deoxy-3-Methyl-
CAS No.	5040-21-1
Molecular Formula	C10H15N3O4
Molecular Weight	241.25 g/mol
Synonyms	3-Methyldeoxycytidine; 3-Methyl-2'-deoxycytidine; 2'-Deoxy-3-methylcytidine; 1-(2-Deoxy-β-D-ribofuranosyl)-3-methyl-2-oxo-1,2-dihydropyrimidin-4-amine; 3-Methyl-1-(2-deoxy-β-D-ribofuranosyl)cytosine; 3-Methyl-dC; 3-Me-dC
EINECS	Contact for details

Quality Control

Our 2'-Deoxy-3-Methylcytidine is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and loss on drying analysis. We provide Certificates of Analysis (COA) with each shipment, detailing all test results to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.