Description

Folcisteine is a synthetic organic compound belonging to the class of cysteine derivatives, recognized for its role as a mucolytic agent and precursor in pharmaceutical synthesis. Its primary value lies in its ability to act as a thiol donor, facilitating the breakdown of disulfide bonds in mucus proteins, which is critical for developing effective respiratory therapeutics. This makes it an essential intermediate for manufacturers in the pharmaceutical and fine chemical industries, particularly for producing expectorant drugs and advanced active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of mucolytic drugs and other sulfur-containing active pharmaceutical ingredients (APIs).
• Respiratory Therapeutics: Used in research and development of formulations aimed at treating chronic obstructive pulmonary disease (COPD), bronchitis, and cystic fibrosis.
• Biochemical Research: Serves as a standard or reagent in studies involving thiol-disulfide exchange, protein structure, and antioxidant mechanisms.
• Fine Chemical Synthesis: Employed as a building block for creating more complex molecules in medicinal chemistry and custom synthesis projects.
• Veterinary Medicine: Potential application in developing respiratory treatments for animals.

Basic Information

Item	Detail
Product Name	Folcisteine
CAS No.	5025-82-1
Molecular Formula	C5H9NO3S
Molecular Weight	163.19 g/mol
Synonyms	L-Folcisteine; S-Carboxymethyl-L-cysteine; Carbocisteine; S-Carboxymethylcysteine; Mucolytic Agent; (R)-2-Amino-3-(carboxymethylthio)propanoic acid; L-Carbocisteine; Transbronchin
EINECS	225-710-2

Quality Control

Our Folcisteine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, IR for identification, and tests for residual solvents and heavy metals. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with in-house specifications and supporting its use in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.5%
Optical Rotation	-90° to -95° (c=1 in 1N HCl)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.