Description

Cyclobutanecarbonyl Chloride is a versatile and highly reactive organic acid chloride building block. Its strained four-membered ring structure makes it a valuable intermediate for introducing the cyclobutyl moiety into more complex molecules, enabling the synthesis of novel compounds with tailored properties. This chemical is essential for research and development in the pharmaceutical and agrochemical industries, where it is used to create active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of novel drug candidates targeting central nervous system (CNS) disorders, antiviral agents, and anti-inflammatory compounds.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclobutyl group can enhance biological activity and environmental profile.
• Material Science Research: Serves as a precursor for monomers and polymers with unique thermal and mechanical properties, contributing to the development of specialty plastics and coatings.
• Organic Synthesis Reagent: Employed in academic and industrial R&D labs for acylation reactions, facilitating the construction of complex organic frameworks, including natural product analogs and functional materials.
• Ligand and Catalyst Development: Utilized to synthesize novel ligands and organometallic complexes for catalytic applications in asymmetric synthesis and cross-coupling reactions.

Basic Information

Product Name	Cyclobutanecarbonyl Chloride
CAS No.	5006-22-4
Molecular Formula	C5H7ClO
Molecular Weight	118.56 g/mol
Synonyms	Cyclobutanecarboxylic Acid Chloride; Cyclobutylcarbonyl Chloride; Cyclobutanoyl Chloride; Cyclobutanecarboxylic Chloride; 1-Cyclobutanecarbonyl Chloride; Cyclobutane-1-carbonyl Chloride; Cyclobutanecarboxychloride; Cyclobutyl Carbonyl Chloride
EINECS	225-674-6

Quality Control

Our Cyclobutanecarbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 2-8°C or as specified on the label. Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.