Description

15α,21-Dihydroxypregn-4-Ene-3,20-Dione (CAS NO 599-17-7) is a key synthetic steroid intermediate with significant relevance in pharmaceutical research and development. Its precise molecular structure makes it a valuable building block for the synthesis of more complex corticosteroid and progestogen analogs. This compound is primarily sought after by research institutions and pharmaceutical manufacturers engaged in steroid chemistry, drug discovery, and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) within the corticosteroid and progestogen classes.
• Biochemical Research: Used as a reference standard or starting material in studies investigating steroid hormone metabolism, receptor binding, and biological activity.
• Process Development: Serves as a key intermediate for optimizing and scaling up synthetic routes for steroid-based therapeutics in pilot plants and manufacturing facilities.
• Academic Research: Employed in university and institutional laboratories for synthetic organic chemistry projects and the development of novel steroid derivatives.

Basic Information

Product Name	15α,21-Dihydroxypregn-4-Ene-3,20-Dione
CAS No.	599-17-7
Molecular Formula	C21H30O4
Molecular Weight	346.46 g/mol
Synonyms	15α,21-Dihydroxyprogesterone; 15α-Hydroxy-21-deoxycortisol; 15α,21-Dihydroxypregn-4-ene-3,20-dione; 15α-Hydroxy-21-deoxycorticosterone; 15α,21-Dihydroxy-4-pregnene-3,20-dione; 15α-Hydroxy-21-desoxycorticosterone; 15α,21-Dihydroxy-δ4-pregnene-3,20-dione
EINECS	Contact for details

Quality Control

Our 15α,21-Dihydroxypregn-4-Ene-3,20-Dione is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.