Description

20,22-Dihydroxycholesterol is a key sterol derivative and an important intermediate in the biosynthesis of steroid hormones. This compound is valued for its role as a research chemical and a precursor in the synthesis of more complex bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of fine chemicals and reference standards for metabolic studies and analytical applications.

Application

• Pharmaceutical Research & Development: Critical intermediate in the synthesis and study of steroid hormones and their metabolic pathways.
• Biochemical Research: Used as a substrate or standard in enzymatic studies related to cholesterol metabolism and steroidogenesis.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in HPLC, LC-MS, and other chromatographic techniques.
• Fine Chemical Synthesis: A building block for the preparation of more complex steroidal compounds with potential biological activity.
• Academic Studies: Employed in university and institutional labs for investigating lipid biochemistry and cell signaling mechanisms.

Basic Information

Product Name	20,22-Dihydroxycholesterol
CAS No.	596-94-1
Molecular Formula	C27H46O3
Molecular Weight	418.66 g/mol
Synonyms	(20R,22R)-20,22-Dihydroxycholesterol; 5-Cholestene-3β,20,22-triol; 20,22-Dihydroxycholest-5-en-3β-ol; 20,22-Dihydroxy-5-cholesten-3β-ol; 3β,20,22-Trihydroxycholest-5-ene; Cholesterol 20,22-diol; 20,22-Dihydroxycholesterol (20R,22R)-isomer
EINECS	Contact for details

Quality Control

Our 20,22-Dihydroxycholesterol is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant research and development standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.