Description

12-Fluoro-2-Dodecanone is a specialized fluorinated ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring a terminal fluorine atom and a ketone group on a long alkyl chain, makes it a valuable precursor for creating complex molecules with tailored properties. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications requiring the introduction of fluorine or specific hydrophobic ketone functionalities.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for introducing fluorinated alkyl chains to modulate bioavailability, metabolic stability, and lipophilicity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental persistence.
• Liquid Crystal & Advanced Material Precursor: Acts as a building block for fluorinated liquid crystals, surfactants, and polymers, contributing to unique dielectric and surface properties.
• Organic Synthesis Reagent: Employed in various carbon-carbon bond forming reactions and as a starting material for synthesizing more complex fluorinated compounds like acids, alcohols, and amines.
• Surface Modification Agent: Utilized to create fluorinated self-assembled monolayers (SAMs) on surfaces to impart oil- and water-repellent characteristics.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing specific, long-chain fluorinated aroma chemicals, though this application is highly specialized.

Basic Information

Product Name	12-Fluoro-2-Dodecanone
CAS No.	593-09-9
Molecular Formula	C₁₂H₂₃FO
Molecular Weight	202.31 g/mol
Synonyms	2-Dodecanone, 12-fluoro-; 12-Fluorododecan-2-one; 1-Fluoro-10-undecanone; ω-Fluoroundecyl methyl ketone; 10-(Fluoromethyl) decan-2-one; 2-Oxododecyl fluoride; Fluorododecanone
EINECS	Contact for details

Quality Control

Our 12-Fluoro-2-Dodecanone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports development from laboratory to commercial scale, ensuring reliable supply for critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.435 - 1.445
Density (g/mL, 20°C)	0.92 - 0.96

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.